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Workshops

Interactions and Transport of Charged Species in Bulk and at Interfaces

July 4, 2016 to July 7, 2016
Location : CECAM-AT

Super Resolution Tractography and Its Application to Neuroscience – Study of Human Language and Emotion

Jang-Hee Cho


Abstract

Superior longitudinal fasciculus (SLF), the well known dorsal fiber believed to be the major language pathway as well as for the movement and cognitive function, which often includes the arcuate fasciculus (AF) as well as superior fronto-occipital (SFO) fasciculus. More recently, sub-components of the SLF have been designated such as SLF I, II, III, and AF. Although substantially thorough investigations have been made including the MRI diffusion tensor imaging (DTI) as well as non-human primates, details of the SLF in human remains unclear and not well understood due to the limited resolution of those previous DTI studies.
Considering the importance of the roles and functions that the SLF is playing in the neural circuitry, especially in the field of the language processing as well as in movement controls and cognitive functions as a part of dorsal stream in the human brain, it would be a worth while endeavor to study in depth such as the exact locations and putative functional roles based on the known cytoarchitectonic as well as receptoarchitectonic knowledge together with functional MRI experimental data and the connectivity map we have obtained with the DTI data of 7.0T MRI.
In this talk, therefore, I will present the fiber structures and connectivity of the SLF in details with newly developed super-resolution tractography obtained from the ultra high field 7.0T MRI. In addition to the microstructural analysis, I will present a putative functionally relevant ¡°functional-connectivity map¡± with which one can analyze or identify, for example, expected roles of the cognitive and language circuitry.